|
KMID : 0359920080270060726
|
|
Korean Journal of Nephrology
2008 Volume.27 No. 6 p.726 ~ p.732
|
|
|
The Effectiveness of Sequential Intravenous Saline and Oral Water Loading Tests and Barsoum-Levine Formula for Managing Hyponatremic Patients: 2 Case Reports
|
|
Yi Joo-Hark
Kim Won-Jun
Noh U-Seok
Kim Yeon-Jae
Ko Young-Sun
Han Sang-Woong
Kim Ho-Jung
|
|
|
Abstract
|
|
|
In hyponatremic patients, the assessment of extracellular fluid volume plays an essential step in diagnosing the etiology of hyponatremia and deciding how to manage it. Although various laboratory tests and diagnostic procedures have been developed for differential diagnosis of hyponatremia, there still are limits to the evaluation of the status of extracellular fluid volume due to the data that overlaps each other, leading to the difficulty in diagnosing between euvolemia and hypovolemia. Also, there is no consensus about how to guide the type and amount of fluid therapy despite many formulas including Adrogue-Madias and Barsoum-Levine formulas have been suggested. Hereby, we are reporting two hyponatremic patients (102 and 105 mEq/L) admitted simultaneously with indistinct volume status on initial clinical and laboratory examinations, but were clarified as euvolemic hyponatremia (syndrome of inappropriate antidiuretic hormone secretion) in one and hypovolemic hyponatremia in the other case after sequential intravenous saline (2 L over 24 hrs) and oral water (20 mL/kg) loading tests. When serum sodium values calculated by the above-mentioned two formulas were compared with actually measured ones during saline loading test in these cases, the Barsoum-Levine formula revealed
almost no discrepancy between both the values while the Adrogue-Madias formula underestimated the measured value.
|
|
|
KEYWORD
|
|
|
Hyponatremia, Formula, Inappropriate ADH syndrome
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|